Benzoyl Chloride

CAS #:  98-88-4

Synonyms:  Alpha-chlorobenzadehyde; Benzenecarbonyl chloride;  Benzoic Acid Chloride

Uses: Introduction of benzoyl group, dye intermediates, benzoyl peroxide manufacturing, analytical reagent

Hazard: Highly toxic. Strong irritant to skin, eyes and mucous membranes, and via ingestion, inhalation.  INHALATION: may irritate eyes, nose and throat. INGESTION: causes acute discomfort. SKIN: causes irritation and burning.  BENZOYL CHLORIDE reacts violently with protic solvents such as alcohols, with amines and amides (for example dimethylformamide [Bretherick 1979 p. 6] ) and with inorganic bases. Causes the violent decomposition of dimethyl sulfoxide. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts. Friedel-Crafts acylation of naphthalene using benzoyl chloride, catalyzed by AlCl3, must be conducted above the melting point of the mixture, or the reaction may be violent .